CHOC Docs :: Provider Profile

Jeff Buzby, PhD

(714) 509-8368


Research Focus:
Molecular & cellular mechanisms that regulate inflammation and coagulation in newborn infants

Immune & Inflammatory Disease Research Lab - CHOC Research Institute
1201 W La Veta
Orange, CA 92868
phone: (714) 509-8368
fax: (714) 509-8698
map & directions

Physician / Researcher Bio

Dr. Buzby received his Ph.D. in Biochemistry from Penn State University. He completed Postdoctoral Fellowships at Penn State and UCLA before joining the CHOC Research Institute Faculty as an Immune & Inflammatory Disease Research Scientist


His research focuses on discovering the molecular & cellular mechanisms that regulate inflammation and coagulation in newborn infants. Since the neonatal immune and coagulation systems are not completely mature, newborn infants are often susceptible to life-threatening complications of severe infection or injury. Identifying genetic vulnerabilities may allow us to protect those newborn infants at risk for such infectious or bleeding complications.

The goal of this research is to find answers to the following questions:

  • What immunological traits are unique to newborn infants & young children
  • How do these traits contribute to inflammatory disease
  • How can this knowledge be applied to discovering new diagnostic & therapeutic tactics for fighting these childhood diseases

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UC Irvine

CHOC Children's is affiliated with the UC Irvine School of Medicine