Richard Chang, MD is a member of the CHOC Children's Specialists Metabolic Disorders division and is board certified in pediatrics. Dr. Chang completed his residency training at Children's Hospital of Orange County and attended medical school at the University of Iowa School of Medicine. Dr. Chang is the assistant division chief of Metabolic Disorders at CHOC Children's. His interests are in the presentation, diagnosis, and treatment of inborn errors of metabolism. Dr. Chang serves as a physician informaticist at CHOC Children's Hospital where he serves as a consultant for electronic health record implementation to enhance health care delivery. Dr. Chang is an Assistant Clinical Professor with the University of California, Irvine School of Medicine Dr. Chang speaks Mandarin Chinese and Taiwanese Chinese.
Wang RY, Chang R, Sowa M, Chang A, Abdenur JE. Prevention of metabolic decompensation in an infant with mutase deficient methylmalonic aciduria undergoing cardiac surgery requiring cardiopulmonary bypass. Submitted. World Journal of Pediatrics. Jan 2013.
Miyake N, Yano S, Sakai C, Hatakeyama H, Matsushima Y, Shiina M, Watanabe Y, Bartley J, Abdenur JE, Wang RY, Chang R, Tsurusaki Y, Doi H, Nakashima M, Saitsu H, Ogata K, Goto YI, Matsumoto N. Mitochondrial Complex III Deficiency Caused by a Homozygous UQCRC2 Mutation Presenting with Neonatal-Onset Recurrent Metabolic Decompensation. Hum Mutat. 2012 Dec 19. doi: 10.1002/humu.22257. [Epub ahead of print]
Williams TB, Daniels M, Puthenveetil G, Chang R, Wang RY, Abdenur JE. Neonatal Diabetes and Adrenal Insufficiency as early manifestations of Pearson Syndrome. Molecular Genetics and Metabolism. 2012, 106(1)104-7.
Friedman J, Roze E, Abdenur JE, Chang R, Gasperini S, Saletti V, Wali GM, Eiroa H, Neville B, Felice A, Parascandalo R, Zafeiriou DI, Arrabal-Fernandez L, Dill P, Eichler FS, Echenne B, Gutierrez-Solana LG, Hoffmann GF, Hyland K, Kusmierska K, Tijssen MAJ, Lutz T, Mazzuca M, Penzien J, Poll-The BT, Sykut-Cegielska J, Szymanska K, Thöny B, Blau N. Sepiapterin Reductase Deficiency: a treatable mimic of cerebral palsy. Annals of Neurology. 2012, 71(4):520-30.
Sass JO, Fischer K, Wang R, Christensen E, Scholl-Bürgi S, Chang R, Kapelari K, Walter M. D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK). Hum Mutat. 2010 Dec;31(12):1280-5. doi: 10.1002/humu.21375.
Puckett RL, Orsini JJ, Pastores GM, Wang RY, Chang R, Saavedra-Matiz CA, Torres PA, Zeng B, Caggana M, Lorey F, Abdenur JE. Krabbe Disease: Clinical, Biochemical and Molecular Information on Six New Patients and Successful Retrospective Diagnosis Using Stored Newborn Screening Cards. Molecular genetics and Metabolism, 105 (1):126-31
Puckett R, Sowa M, Lorey F, Levine S, Rinaldo P, Lipson M, Matern D, Sowa M, Levine S, Chang R, Wang R, Abdenur JE. Maple syrup urine disease (MSUD) : Further evidence that variant forms cannot be detected by newborn screening (NBS). MGM 2010; 100: 136-142
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