CHOC Docs :: Provider Profile

Michele B Domico, MD


Critical Care

Board Certified:
Pediatrics, Critical Care Medicine


Dr. Domico is on staff at CHOC Children's Hospital & CHOC Children's at Mission Hospital

CHOC Children's Hospital
1201 W. La Veta Ave.
Orange, CA 92868
map & directions

CHOC Children's at Mission Hospital
27700 Medical Center Rd
Mission Viejo, CA 92691
map & directions

Hoag Memorial Presbyterian Hospital
1 Hoag Dr
Newport Beach, CA 92663
map & directions

Physician Bio

Dedicated to her field, Dr. Domico provides the full range of critical care procedures, with expertise in pediatric cardiac intensive care. She has published several clinical research articles, including studies on extracorporeal life support and research related to cardiac intensive care. She has spearheaded multiple quality improvement projects in the cardiac intensive care unit at CHOC to ensure improved patient safety and outcomes. She also serves as a reviewer for Pediatric Critical Care Medicine journal.

Dr. Domico is board certified in both pediatrics and pediatric critical care medicine. Dr. Domico worked in London at the world-renowned Great Ormond Street Hospital for Children as a Senior Fellow in pediatric cardiac intensive care/ ECMO. She completed her pediatric critical care fellowship at Harbor-UCLA Medical Center and Children's Hospital of Orange County. She received additional fellowship training in pediatric cardiology at the University of Florida Health Science Center. Dr. Domico attended medical school and completed her internship and residency at University of Texas Health Science Center in San Antonio. She is currently the Medical Director of the Cardiac Intensive Care Unit at CHOC, and the Medical Director of the ECMO program.

Administrative Appointments

  • Critical Care, CHOC Children's Specialists
  • Assistant Clinical Professor, Pediatrics
    University of California, Irvine Medical Center

Academic Appointments

  • Assistant Clinical Professor, Pediatrics
    Harbor-UCLA Medical Center


  • Medical School
    University of Texas Health Science Center
  • Residency
    University of Texas Health Science Center
  • Fellowship
    University of Florida Health Science Center
    Harbor-UCLA Medical Center/Children’s Hospital of Orange County
    Great Ormond Street Hospital for Children

Board Certifications

  • Pediatrics
    American Board of Pediatrics
  • Critical Care Medicine
    American Board of Pediatrics

Professional Organizations

  • Pediatric Cardiac Intensive Care Society
  • Society of Critical Care Medicine
  • American Academy of Pediatrics

Published Works

Domico M, Mink R, Anas N, Chang AC, Bronicki R: Nesiritide in pediatric cardiac intensive care: Evidence for improved renal function. Manuscript in progress, planned submission to Pediatric Cardiology

Domico M, Ridout D, Bronicki R, Anas N, Cleary J, Cappon J, Goldman A, Brown K: The impact of mechanical ventilation time prior to the initiation of ECLS on survival in pediatric respiratory failure: A review of the ELSO Registry. Pediatric Critical Care Medicine 2012; 13: p16- 21

Domico, M, Checchia P: Biomonitors of cardiac injury and performance: B-type natriuretic peptide and troponin as monitors of hemodynamics and oxygen transport balance. Pediatric Critical Care Medicine 2011; 12: 33-42 (suppl)

Bronicki , Herrera M, Mink R, Domico M, Tucker D, Chang A, Anas N: Hemodynamics and Cerebral Oxygenation following repair of Tetralogy of Fallot: The Effects of Converting from Positive Pressure Ventilation to Spontaneous Breathing. Congenital Heart Disease 2010; 5:416-421

Domico M, Chang AC: ECHO for ECMO: Not Just for Cardiac Function. Pediatric Critical Care Medicine 2009; 10(1): 138

Lectures and Presentations

  • What biomarkers can help us in the Cardiac Intensive Care Unit
  • Does cardiac dysfunction preclude the use of VV ECMO?
  • ECLS in pediatric respiratory failure and predictors of outcome including duration of mechanical ventilation

Facebook  Twitter  Pinterest  Instagram  Foursquare
 LinkedIn  YouTube  RSS  CHOC Blog


UC Irvine

CHOC Children's is affiliated with the UC Irvine School of Medicine