CHOC Docs :: Provider Profile

Elyssa Rubin, MD

(714) 509-8636


Board Certified:
Pediatrics, Pediatric Hematology/Oncology

Special Interests:
Sarcomas, neuroblastoma and the histiocytic disorders

Dr. Rubin is on staff at CHOC Children's Hospital

Outpatient Clinic, Hyundai Cancer Institute at CHOC Children's
1201 W. La Veta Ave.
Orange, CA 92868
phone: (714) 509-8636
fax: (714) 509-8699
map & directions

Physician / Researcher Bio

With special interests in sarcomas, neuroblastoma and the histocytic disorders, Dr. Elyssa Rubin serves as the director of the Bone and Soft Tissue Tumor Program at CHOC Children’s and is an oncologist with CHOC Children's Specialists.

Dr. Rubin is board certified in pediatrics and pediatric hematology/oncology. Dr. Rubin completed her medical school training at the Sackler School of Medicine, NY State/American Branch in Tel Aviv, Israel. She completed her pediatric internship and residency training at Kaiser Permanente Los Angeles Medical Center and her fellowship in pediatric hematology/oncology at Children's Hospital of Orange County. As a research fellow, Dr. Rubin’s focus was on new therapeutic targets for osteosarcoma.

Administrative Appointments

  • Oncology, CHOC Children's Specialists
  • Director, Bone and Soft Tissue Tumor Program, CHOC Children's Hyundai Cancer Institute

Academic Appointments

  • Assistant Professor of Pediatrics
    University of California, Irvine, School of Medicine


  • Fellowship
    Pediatric Hematology and Oncology at Children's Hospital of Orange County, Orange,California
  • Pediatric Internship and Residency
    Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
  • Medical School
    Sackler School of Medicine, NY State/American Branch, Tel Aviv, Israel

Board Certifications

  • Pediatrics
    American Board of Pediatrics
  • Pediatric Hematology/Oncology
    American Board of Pediatrics

Professional Organizations

  • Children’s Oncology Group (COG)
  • Connective Tissue Oncology Society (CTOS)
  • Histiocyte Association of America (HAA)
  • American Society of Clinical Oncology (ASCO)
  • American Society of Pediatric Hematology and Oncology (ASPHO)
  • American Society for Blood and Marrow Transplantation (ASBMT)
  • American Association for Cancer Research (AACR)

Published Works

Buchbinder, D., Hsieh, L., Puthenveetil G., Soni A., Stites J., Huynh V., Kirov I., Neudorf S., Rubin E., Sender L., Torno L., Margolis D., Childs R., Moore T., Nugent D. Successful Autologous cord blood transplantation in a child with acquired severe aplastic anemia. Pediatr Transplant, 2013 May;17(3):E104-7. Doi: 10.1111/petr.12068. Epub 2013 Mar 7.

McQueen P, Ghaffar S, Guo Y, Rubin EM, Zi X, Hoang BH. The Wnt signaling pathway: implications for therapy in osteosarcoma. Expert Review of Anticancer Therapy. 11(8):1223-32 (2011). PMID 21916576

Rubin EM, Guo Y, Tu K, Xie J, Zi X, Hoang BH. Wnt inhibitory factor 1decreases tumorigenesis and metastasis in osteosarcoma, Mol Cancer Ther. 2010 Mar:9(3):731-41. Epub 2010 Mar 2. PMID: 20197388

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UC Irvine

CHOC Children's is affiliated with the UC Irvine School of Medicine