CHOC Docs :: Provider Profile

Antoine "Tony" E Khoury, MD




Board Certified:


Dr. Khoury is on staff at CHOC Children's Hospital

CHOC Children's Urology Center
505 S Main St
Orange, CA 92868
phone: 714-509-3919
fax: 866-529-9704
map & directions

UC Irvine Health
333 City Blvd W
Orange, CA 92868
map & directions

Physician Bio

A world-renowned expert in pediatric urology, Dr. Khoury specializes in the medical and surgical management of complex pediatric urology anomalies, including reconstructive surgery for incontinence, genital anomalies, renal transplantation and oncology. Dr. Khoury is the chief of pediatric urology at both CHOC Children’s and UC Irvine Medical Center.

Dedicated to clinical excellence, Dr. Khoury is board certified in urology. Prior to joining CHOC Children’s, Dr. Khoury received his medical degree at Ain Shams University in Cairo, Egypt and completed a residency in urology at the University of Toronto. Dr. Khoury completed his clinical fellowship and a research fellowship in pediatric urology at the Hospital of SickKids in Toronto, Canada followed by a research fellowship at the University of Calgary, where he focused on biomaterial-related infections. Dr. Khoury speaks fluent French and Arabic.

Administrative Appointments

  • Chair, Urology, CHOC Children's
  • Medical Director, Urology, CHOC Children’s
  • Chief, Pediatric Urology, UC Irvine Medical Center

Academic Appointments

  • Professor, Department of Surgery, University of Toronto, Toronto, Ontario
  • Professor, Urology, University of California Irvine, Orange, California


  • Medical School
    Ain Shams University, Cairo, Egypt
  • Residency - Urology
    University of Toronto, Canada
  • Fellowship - Pediatric Urology
    Hospital for Sick Children, Toronto, Canada
  • Research Fellowship - Pediatric Urology
    Hospital for Sick Children, Toronto, Canada
  • Research Fellowship - Biomaterial-Related Infections
    University of Calgary, Alberta, Canada

Board Certifications

  • Urology

Honors and Awards

  • Orange County Urological Association Award: 1st Prize Guy Hidas for Aerosol Transfer of Blader Urothelial and Smooth Muscle Cells onto Demucosalizsed Colonic Sements for Bladder Augmentation in Vivo: Long Term and Functional Results
  • Orange County Urological Association Award: 3rd Prize Guy Hidas for Is the Appearance of the Deflux Mound Predictive of Reflux Resolution?

Professional Organizations

  • American Academy of Pediatrics
  • American Association of Genitourinary Surgeons
  • American Urological Association
  • American Urology Association
  • Canadian Urological Association
  • Cochrane Renal Group
  • International Continence Children's Society
  • National Institute of Child Health and Human Development of the National Institute of Health
  • North American Task Force on Intersexuality (NATFI)
  • World Health Organization (WHO)- International Union Against Cancer (UICC)

Published Works

Khoury AE, Dave S, Peralta-Del Valle MH, Braga LH, Lorenzo AJ, Bägli D.BJU Severe bladder trabeculation obviates the need for bladder outlet procedures during augmentation cystoplasty in incontinent patients with neurogenic bladder. BJU Int. Jan 2008 Pages 223-226

Braga LH, Lorenzo AJ, Bägli DJ, Khoury AE, Pippi Salle JL. Outcome analysis of Isolated male epispadias: single center experience with 33 cases, Journal of Urology March 2008 Pages: 1107-12

Dave S, Pippi Salle JL, Lorenzo AJ, Braga LH, Peralta-Del Valle MH, Bägli D, Khoury AE. Is Long- Term bladder deterioration ineveitable following successful isolated bladder outlet procedures in children with neuopathic bladder dysfunction Journal of Urology May 2008 Pages 1991-1996

Wallis MC, Lorenzo AJ, Farhat WA, Bägli DJ, Khoury AE, Pippi Salle JL. Risk assessment of incidentally detected complex renal cysts in children potential role for a modification of the Bosniak classification. Journal of Urology July 2008 Pages 317-321

Al-Mandil M, Khoury AE, El-Hout Y, Kogon M, Dave S, Farhat WA. Potential Complications with the prescrotal approach for the palpable undescended testis A comparison of single prescrotal incision to the traditional inguinal approach. Journal of Urology August 2008 vol. 180 Pages: 686-689 Pippi Salle JL, Cook A, Papanikolaou F, Bägli D, Breen SL, Charron M, Braga LH, Lorenzo AJ, Khoury AE. The importance of obtaining conjugate views on renographic evaluation of large hydronephrotic kidneys: and invitro and exvivo analysis. Journal of Urology October 2008 Volume 180 Pages 1559-65

Braga LH, Lorenzo AJ, Bagli DJ, Dave S, Eeg K, K. Frahat WA, Pippi Salle JL, Khoury AE. Ventral penile lengthening versus dorsal plication for severe ventral curvature in children with proximal hypospadias. J Urol.Oct 2008 180 (4 Suppl):1743-7; discussion 1747-8

209. Dave S, Lorenzo AJ, Khoury AE, Braga LH, Skeldon SJ, Suoub M, Farhat W, Pippi Salle JL, Bägli DJ. Learning from the learning curve: factors associated with successful endoscopic correction of vesicoureteral reflux using dextranomer/hyaluronic acid copolymer. J Urol. Oct 2008 180 (4 Suppl):1594-9; discussion 1599-600 Braga LH, Lorenzo AJ, Bägli DJ, Keays M, Farhat WA, Khoury AE, Salle JL. Risk factors for recurrent ureteropelvic junction obstruction after open pyeloplasty in a large pediatric cohort.J Urol. Oct 2008 180(4 Suppl):1684-7; discussion 1687-8

Dave S, Khoury AE, Braga L, Farhat WA. Single “institutional study on role uretersocopy and retrograde intrarenal surgery in treatment of pediatric renal calculi. Journal of Urology Urology Nov 2008 Volume 72, Pages 1018-21

Kurt R. Eeg, Antoine E Khoury, Sarel Halachmi, Luis H.P. Braga, Walid A. Farhat, Darius J. Bägli, Joao L. Pippi Salle, Armando J. Lorenzo Single Center Experience With Application of the ALARA Concept to Serial Imaging Studies After Blunt Renal Trauma in Children Is Ultrasound Enough The Journal of Urology April 2009 (Vol. 181, Issue 4, Pages 1834-1840)

Dave S, Manaboriboon N, Braga LH, Lorenzo AJ, Farhat WA, Bägli DJ, Khoury AE, Salle JL. Open versus laparoscopic staged fowler- stephens orchiopexy: impact of long loop vas. Journal of Urology Nov 2009 Volume 182 pages 2435-2439

Antoine E. Khoury Reoperative Hypospadias: More than just the Urethra The Journal of Urology December 2009 (Vol. 182, Issue 6, Pages 2559-2560)

Braga LHP , Lorenzo AJ Bagli DJ , Mahdi M , Salle JLP , Khoury AE Farhat WA Comparison of Flank, Dorsal Lumbotomy and Laparoscopic approaches for dismembered pyeloplast in children older than 3 years with ureteropelvic junction obstruction. Journal of Urology Jan 2010 Volume 183 pages 306-311

Wright JG, Roche A, Khoury AE Improving on-time surgical starts in an operating room. Can J Surg. 2010 Jun;53(3):167-70

Skoog SJ, Peters CA, Arant BS Jr, Copp HL, Elder JS, Hudson RG, Khoury AE, Lorenzo AJ, Pohl HG, Shapiro E, Snodgrass WT, Diaz M. Pediatric Vesicoureteral Reflux Guidelines Panel Summary Report: Clinical Practice Guidelines for Screening Siblings of Children With Vesicoureteral Reflux and Neonates/Infants With Prenatal Hydronephrosis. J Urol. 2010 Sep;184(3):1145-51

Peters CA, Skoog SJ, Arant BS Jr, Copp HL, Elder JS, Hudson RG, Khoury AE, Lorenzo AJ, Pohl HG, Shapiro E, Snodgrass WT, Diaz M. Summary of the AUA Guideline on Management of Primary Vesicoureteral Reflux in Children. Journal of Urology Sept 2010; 184 (3): 1134-44

Leslie B, Moore K, Salle JL, Khoury AE, Cook A, Braga LH, Bägli DJ, Lorenzo AJ Outcome of antibiotic prophylaxis discontinuation in patients with persistent vesicoureteral reflux initially presenting with febrile urinary tract infection: time to event analysis. Journal of Urology Sept 2010; 184 (3): 1093-8

Hidas G, Watts B, Khoury AE The evolving role of laparoscopic surgery in paediatric urology. Arab Journal of Urology (2012) 10, 74-80

Hidas G, Soltani T, Watts B, Pribish M, Khoury AE.Is the Appearance of the Dextranomer/Hyaluronic Acid Mound Predictive of Reflux Resolution J Urol. 2012 Nov 27. doi:pii: S0022-5347(12)05619-4. 10.1016/j.juro.2012.11.110. [Epub ahead of print] PMID: 23201379 [PubMed - as supplied by publisher]

Khoury, AE, Hidas G. Primary Vesico-ureteric reflux: The need for individualized risk stratification Reference: AJU138, Arab Journal of Urology, Jan 24,201310.1016/j.aju.2012.11.006

Khoury, AE, Hidas, G Application of Continuous Incisional Infusion of Local Anesthetic after Major Pediatric Urological Surgery Reference: JPUROL1373 S1477-5131(13)00014-4 10.1016/j.jpurol.2013.01.007

Khoury, AE, Hidas, G. Management of Rectal Stenosis with Endoscopic Ballon Dilatation Journal of Pediatric Surgery Journal of Pediatric Surgery: S0022-3468(13)00046-8 10.1016/j.jpedsurg.2013.01.035

Presentations and Abstracts

El-Hout, Licht C, Eeg KR, Lorenzo AJ, Salle JLP, Bagli DJ, Khoury AE, Farhat WA: Hypertension in children with poorly functioning kidney: Predictors of resolution after nephrectomy: Journal of Urology Volume: 179 Issue: 4 Pages: 412-412 Supplement: Suppl. S Published: APR 2008

Braga LH, Lorenzo AJ, Ei-Hout Y, Farhat WA, Bagli DJ, Khoury AE, Salle JLP: Should we still use Onlay Island Flap for penoscrotal hypospadias repair Source: Journal of Urology Volume: 179 Issue: 4 Pages: 408-409 Supplement: Suppl. Published: APR 2008

Al Mandil M, Khoury AE, Souab Mm,Farhat WA, Salle JLP: Referral pattern of primary undescended testes to a childern hospital in North America: Are we meeting the current recommendation in the management of cryptorchidism : Source: JOURNAL OF UROLOGY Volume: 179 Issue: 4 Pages: 145-145 Supplement: Suppl. S Published: APR 2008

Braga L H, Lorenzo AJ, Jrearz R., Bagli DJ, Farhat W, Salle JLP, Khoury AE: Gender-based outcome analysis after complete primary repair of bladder exstrophy (CPRE): Source: Journal of Urology Volume: 179 Issue: 4 Pages: 95-95 Supplement: Suppl. S Published: APR 2008

Braga L H, Lorenzo AJ, Jrearz R, Bagli DJ, Farhat W, Salle JLP, Khoury AE, Suoub, M, Salle, Gabriela, Mahdi, Mohamed, Farhat A Walid: Risk Factors for Fistula Formation (FF) after tip repair: Single Center Multivariable Analysis of 601 Distal Hypospadias.: Source: AAP Joint Pediatric Urology Meeting, October 2008

Braga L H, Lorenzo AJ, Jrearz R, Bagli DJ, Farhat W, Salle JLP, Khoury AE : Does Bilateral Ureteral Reimplantation at the time of primary bladder exstrophy closure (CPRE-BUR) Protect the Upper Tracts Source: AAP Section on Urology, October 2008

Khoury A (Khoury, Antoine): Screening For Reflux - What Price Reassurance Source: Journal of Urology Volume: 181Issue: 2 Pages: 445-446 Published: Feb 2009

Luis H Braga, Armando J Lorenzo, Angela Assal, Bruno Leslie, Walid A Farhat, Darius J Bagli, Joao L Pippi Salle, Antoine E Khoury Increased bladder capacity develops with age, regardless of intial treatment: A single center 15- year longitudinal follow-up study in patients with posterior uretheral valves (PUV) The Journal of Urology April 2009 Vol. 181, Issue 4, Page 172

Bruno Leslie, Katherine Moore, Darius J Bagli, Walid A Farhat, Anthony Cook, Antoine E Khoury, Joao L Pippi-Salle, Aramando J Lorenzo Outcome of antibiotic prophlaxis cessation in patients with persistent vesico-urertal reflux who inittally presented with a febrile urinary tract infection The Journal of Urology April 2009 Vol. 181, Issue 4, Page 223

Yaser El-Hout, Armando J. Lorenzo, Antoine E Khoury, Walid A. Farhat, Darius J Bagli, Joao L. Pippi Salle: Preliminary assessment of a mathematical model to predict penile length after dorsal plication in hypospadias repair. The Journal of Urology April 2009 Vol. 181, Issue 4, Page 115

Antoine Khoury, Improved Cosmetic Outcome for the Clitoral Reduction Component of Feminizing Genitoplasty Journal of Pediatric Urology, Volume 6, Supplement 1, April 2010, Page S87

Armando Lorenzo, Frank Papanikolaou, Joao Pippi Salle, Darius Bagli, Bruno Leslie, Antoine Khoury Development of Macroplastique® Bolus Calcification Detected During Long Term Follow-Up After Injection for Vesico-Ureteral Reflux Journal of Pediatric Urology, Volume 6, Supplement 1, April 2010, Page S29

Liss MA, Khoury A, Dash A. Thirty-three-year-old man presents with abdominal mass with empty scrotum.Urology 2012 Nov; 80(5):971-3. doi: 10.1016/j.urology.2012.08.011. Epub 2012 Sep 19. No abstract available PMID: 22999446 [PubMed - indexed for MEDLINE]

Khoury A.Commentary to 'Long-term incidence of urinary tract infection after ureteral reimplantation for primary vesicoureteral reflux'.J Pediatr Urol. 2012 Aug;8(4):450-1. doi: 10.1016/j.jpurol.2012.02.007. Epub 2012 Apr 11. No abstract available.PMID:22498009 PubMed - indexed for MEDLINE]

Khoury A, Schmid WR.Commentary to 'Long-term results of endoscopic treatment of vesicoureteral reflux in children with different materials'.Pediatr Urol. 2013 Feb;9(1):76-7. doi: 10.1016/j.jpurol.2012.01.006. Epub 2012 Feb 26. No abstract available.PMID:22373654 [PubMed - in process]

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UC Irvine

CHOC Children's is affiliated with the UC Irvine School of Medicine